Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308949 | 0.81 | PPARG (0.38) | GAAFFAR1PPARGMAPTKDM4E | |
| SCHEMBL8308951 | 0.81 | PPARG (0.38) | GAAFFAR1PPARGMAPTKDM4E | |
| SCHEMBL8305071 | 0.78 | PPARG (0.37) | FFAR1PPARGMAPTALDH1A1CTSK | |
| SCHEMBL8305072 | 0.78 | PPARG (0.37) | FFAR1PPARGMAPTALDH1A1CTSK | |
| SCHEMBL8307958 | 0.78 | PPARG (0.38) | FFAR1PPARGKDM4ECTSK | |
| SCHEMBL8307959 | 0.78 | PPARG (0.38) | FFAR1PPARGKDM4ECTSK | |
| SCHEMBL8309388 | 0.78 | PPARG (0.44) | GAAFFAR1PPARGMAPTKDM4E | |
| SCHEMBL8307315 | 0.77 | PPARG (0.36) | FFAR1PPARGMAPTALDH1A1CTSK | |
| SCHEMBL8307312 | 0.77 | PPARG (0.36) | FFAR1PPARGMAPTALDH1A1CTSK | |
| SCHEMBL8306092 | 0.77 | PPARG (0.35) | FFAR1PPARGALDH1A1CTSKRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5780490-A | A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS | SANKYO COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5703096-A | ANTIDIABETIC AGENTS; ALDOSE REDUCTASE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |