SCHEMBL8305067

SCHEMBL8305067

COCC1CN(c2ccc3nc(C(C#N)OC)sc3c2)C(=O)O1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 9/20 0.39
GRM5 P41594 3/20 0.38
MAOB P27338 2/20 0.35
F10 P00742 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3504084 0.85 GRM2 (0.37) GRM2GRM5MAOBF10
SCHEMBL3503313 0.85 GRM2 (0.37) GRM2GRM5MAOBF10
SCHEMBL3504083 0.85 GRM2 (0.37) GRM2GRM5MAOBF10
SCHEMBL3503314 0.85 GRM2 (0.37) GRM2GRM5MAOBF10
SCHEMBL3503318 0.85 GRM2 (0.37) GRM2GRM5MAOBF10
SCHEMBL9186218 0.85 GRM2 (0.37) GRM2GRM5MAOB
SCHEMBL3508402 0.85 GRM2 (0.38) GRM2GRM5MAOBF10
SCHEMBL9185352 0.82 F10 (0.36) GRM2GRM5MAOBF10
SCHEMBL8305866 0.82 MAOB (0.38) GRM2GRM5MAOB
SCHEMBL3505659 0.81 GRM2 (0.39) GRM2GRM5MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609441-B1 Oxazolidone derivatives as monoamine oxidase inhibitors EISAI CO LTD (JP) 1999-07-21 EP disclosed
EP-0609441-A1 OXAZOLIDONE DERIVATIVE Eisai Co., Ltd. (JP) 1994-08-10 EP disclosed