Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3505520 | 0.87 | GRM2 (0.39) | GRM2GRM5MAOB | |
| SCHEMBL8310113 | 0.86 | GRM2 (0.38) | GRM2GRM5MAOB | |
| SCHEMBL3504921 | 0.86 | GRM2 (0.39) | GRM2GRM5MAOB | |
| SCHEMBL3505099 | 0.86 | GRM2 (0.39) | GRM2GRM5MAOB | |
| SCHEMBL3505659 | 0.86 | GRM2 (0.39) | GRM2GRM5MAOB | |
| SCHEMBL3503413 | 0.85 | GRM2 (0.38) | GRM2GRM5MAOB | |
| SCHEMBL3503412 | 0.85 | GRM2 (0.38) | GRM2GRM5MAOB | |
| SCHEMBL3506626 | 0.85 | GRM2 (0.38) | GRM2GRM5MAOB | |
| SCHEMBL8305638 | 0.84 | MAOB (0.42) | GRM2GRM5MAOB | |
| SCHEMBL8303678 | 0.81 | MAPT (0.47) | GRM2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609441-B1 | Oxazolidone derivatives as monoamine oxidase inhibitors | EISAI CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0609441-A1 | OXAZOLIDONE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |