Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 17/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307324 | 0.83 | KDM4E (0.40) | PARP1PIM1CSNK1D | |
| SCHEMBL51055 | 0.79 | PARP1 (0.60) | PARP1PIM1CSNK1D | |
| SCHEMBL51550 | 0.78 | PARP1 (0.66) | PARP1PIM1CSNK1D | |
| SCHEMBL61142 | 0.75 | PARP1 (0.62) | PARP1PIM1CSNK1D | |
| SCHEMBL14213059 | 0.73 | PARP1 (0.62) | PARP1PIM1CSNK1D | |
| SCHEMBL62110 | 0.73 | PARP1 (0.58) | PARP1PIM1CSNK1D | |
| SCHEMBL12658473 | 0.72 | PARP1 (0.69) | PARP1PIM1CSNK1D | |
| SCHEMBL14336605 | 0.72 | PARP1 (0.60) | PARP1PIM1CSNK1D | |
| SCHEMBL51477 | 0.71 | PARP1 (0.61) | PARP1PIM1CSNK1D | |
| SCHEMBL13647432 | 0.71 | PARP1 (0.58) | PARP1PIM1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004105700-A2 | COMPOUNDS, METHODS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PARP | GUILDFORD PHARMACEUTICALS, INC. (US) | 2004-12-09 | — | — | WO | disclosed |