Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 2/20 | 0.38 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825743 | 0.86 | LATS1 (0.37) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6822491 | 0.86 | MAPK1 (0.41) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6825731 | 0.84 | LATS1 (0.38) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6825653 | 0.74 | CYP2A6 (0.45) | MAPTMEN1KMT2AHPGDCTSS | |
| SCHEMBL6825658 | 0.72 | CYP2A6 (0.43) | KMT2ALMNANPSR1LATS1LATS2 | |
| SCHEMBL6827688 | 0.72 | CYP2A6 (0.42) | MAPTMEN1KMT2ACTSSMAPK1 | |
| SCHEMBL6825775 | 0.69 | MAP4K4 (0.40) | DPP4 | |
| SCHEMBL6825776 | 0.68 | MAP4K4 (0.39) | DPP4 | |
| SCHEMBL6825733 | 0.67 | MAP4K4 (0.46) | SYK | |
| SCHEMBL11996132 | 0.64 | GSK3B (0.53) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089950-A1 | TRICYCLIC HETEROAROMATIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-10-21 | — | — | WO | disclosed |