Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344322 | 0.81 | PARP1 (0.57) | PARP1MEN1KMT2ALMNANR3C2 | |
| SCHEMBL8306915 | 0.72 | PARP1 (0.50) | PARP1MEN1KMT2ALMNANR3C2 | |
| SCHEMBL24823314 | 0.72 | PARP1 (0.46) | PARP1KMT2ANR3C2TP53THRB | |
| SCHEMBL8307693 | 0.67 | PARP1 (0.43) | PARP1KMT2ALMNANR3C2TP53 | |
| SCHEMBL560406 | 0.66 | — | — | |
| SCHEMBL3342262 | 0.65 | MMP12 (0.57) | PARP1MEN1KMT2ALMNAPOLB | |
| SCHEMBL3791777 | 0.65 | PARP1 (0.54) | PARP1MEN1KMT2ALMNAMAPT | |
| SCHEMBL12333094 | 0.64 | PARP1 (0.55) | PARP1MEN1KMT2ALMNANR3C2 | |
| SCHEMBL8303332 | 0.63 | PARP1 (0.45) | PARP1MEN1KMT2ANR3C2TP53 | |
| SCHEMBL8303156 | 0.63 | MMP12 (0.57) | PARP1MEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548254-B1 | 6- OR 7-(IMIDAZOLIDIN-2-YLIDENEAMINO)-1,4-BENZOXAZINES AS ALPHA ADRENERGIC AGENTS | ALLERGAN INC (US) | 1999-06-02 | — | — | EP | disclosed |