Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009144 | 0.92 | NPSR1 (0.77) | NPSR1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL8305529 | 0.85 | NPSR1 (0.60) | NPSR1KMT2AGAAHPGDMEN1 | |
| SCHEMBL10683354 | 0.82 | NPSR1 (0.58) | NPSR1KMT2AGAAMEN1KDM4E | |
| SCHEMBL9283221 | 0.80 | NPSR1 (0.72) | NPSR1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL4408532 | 0.78 | NPSR1 (0.74) | NPSR1KMT2AGAAHPGDMEN1 | |
| SCHEMBL30408092 | 0.77 | NPSR1 (0.78) | NPSR1KMT2AGAAHPGDKDM4E | |
| SCHEMBL27797941 | 0.76 | NPSR1 (0.48) | NPSR1KMT2AGAAHPGDMEN1 | |
| SCHEMBL6677714 | 0.75 | NPSR1 (0.54) | NPSR1KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL4008749 | 0.75 | NPSR1 (0.59) | NPSR1KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL27651146 | 0.74 | NPSR1 (0.56) | NPSR1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963983-A1 | Indol-2-ones as serotonin modulators | ELI LILLY AND COMPANY LIMITED (GB) | 1999-12-15 | — | — | EP | disclosed |