Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27797941 | 0.85 | NPSR1 (0.48) | NPSR1HPGDGAAKMT2AMEN1 | |
| Hexane SCHEMBL8305527 | 0.85 | NPSR1 (0.66) | NPSR1HPGDGAAKMT2AMEN1 | |
| SCHEMBL19832964 | 0.78 | NPSR1 (0.44) | NPSR1HPGDGAAKMT2AMEN1 | |
| SCHEMBL4955211 | 0.76 | KCNN4 (0.49) | GAAALDH1A1HTT | |
| SCHEMBL30408092 | 0.76 | NPSR1 (0.78) | NPSR1HPGDGAAKMT2ATP53 | |
| SCHEMBL4009144 | 0.76 | NPSR1 (0.77) | NPSR1HPGDKMT2ATP53LMNA | |
| SCHEMBL28899627 | 0.75 | NPSR1 (0.43) | NPSR1HPGDGAAKMT2AMEN1 | |
| SCHEMBL11805458 | 0.75 | NPSR1 (0.43) | NPSR1HPGDGAAKMT2AMEN1 | |
| SCHEMBL22204543 | 0.75 | NPSR1 (0.51) | NPSR1KMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL4408532 | 0.74 | NPSR1 (0.74) | NPSR1HPGDGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963983-A1 | Indol-2-ones as serotonin modulators | ELI LILLY AND COMPANY LIMITED (GB) | 1999-12-15 | — | — | EP | disclosed |