Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL6842378 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL8031050 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL3310000 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL6439765 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL3307229 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL15020058 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL6439648 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL832069 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL48804 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 | |
| Ethyl Acetate SCHEMBL7919087 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10TSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143411-B2 | Substituted 6-phenylnicotinic acids and their use | BAYER ANIMAL HEALTH GMBH (DE) | 2012-03-27 | — | — | US | disclosed |
| US-20100234432-A1 | Substituted 6-phenylnicotinic acids and their use | BAYER ANIMAL HEALTH GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100099681-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-22 | — | — | US | disclosed |
| US-6194409-B1 | SERINE PROTEASE INHIBITOR; BIOAVAILABILITY WHEN ADMINISTERED BY MOUTH | AKZO NOBEL N.V. (NL) | 2001-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234432-A1 | Substituted 6-phenylnicotinic acids and their use | SLC5A6, FABP3, NAPRT | ALDH1A1 1238/4885LMNA 522/4885HSD17B10 1669/4885 |
| US-20100099681-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | CYP3A5, ABAT, TPMT | ALDH1A1 260/4885LMNA 4322/4885HSD17B10 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.