Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305991 | 0.86 | KDM4E (0.60) | TP53MAPTGAAALDH1A1POLB | |
| SCHEMBL8305695 | 0.85 | TP53 (0.65) | TP53MAPTGAAALDH1A1POLB | |
| SCHEMBL8305815 | 0.84 | KDM4E (0.62) | TP53MAPTGAAALDH1A1POLB | |
| SCHEMBL8305716 | 0.84 | KDM4E (0.62) | TP53MAPTGAAALDH1A1POLB | |
| SCHEMBL8308106 | 0.84 | TP53 (0.58) | TP53GAAALDH1A1POLBBACE1 | |
| SCHEMBL8306950 | 0.82 | KDM4E (0.57) | TP53MAPTGAAALDH1A1POLB | |
| SCHEMBL8308354 | 0.82 | KDM4E (0.51) | TP53MAPTGAAALDH1A1BACE1 | |
| SCHEMBL8305720 | 0.81 | RXFP1 (0.58) | TP53MAPTGAAALDH1A1POLB | |
| SCHEMBL8305992 | 0.81 | RXFP1 (0.66) | TP53MAPTGAAALDH1A1POLB | |
| SCHEMBL8312492 | 0.80 | TP53 (0.63) | TP53MAPTALDH1A1POLBBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |