Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | PPM1D | O15297 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471485 | 0.90 | NAMPT (0.48) | RAB9APKMHPGDOPRM1SMN1; SMN2 | |
| SCHEMBL1470949 | 0.89 | RAB9A (0.47) | RAB9APKMHPGDSMN1; SMN2NPC1 | |
| SCHEMBL1471470 | 0.89 | HPGD (0.48) | RAB9APKMHPGDSMN1; SMN2NPC1 | |
| SCHEMBL1470886 | 0.89 | RAB9A (0.45) | RAB9APKMHPGDSMN1; SMN2NPC1 | |
| SCHEMBL1471258 | 0.88 | RAB9A (0.47) | RAB9APKML3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL1470779 | 0.88 | RAB9A (0.47) | RAB9APKMHPGDSMN1; SMN2NPC1 | |
| SCHEMBL1471433 | 0.88 | HPGD (0.47) | RAB9APKMHPGDSMN1; SMN2NPC1 | |
| SCHEMBL14382950 | 0.88 | HPGD (0.49) | RAB9APKML3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL1473205 | 0.88 | RAB9A (0.53) | RAB9APKML3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL1471333 | 0.88 | RAB9A (0.49) | RAB9APKMHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021525-A1 | ARYL PIPERIDINE AMIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-10 | — | — | WO | disclosed |