Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.70 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.70 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314345 | 1.00 | PRSS1 (0.70) | PRSS1TPSAB1F2 | |
| SCHEMBL5634902 | 1.00 | PRSS1 (0.70) | PRSS1TPSAB1F2 | |
| SCHEMBL4314363 | 1.00 | PRSS1 (0.70) | PRSS1TPSAB1F2 | |
| SCHEMBL5634690 | 1.00 | PRSS1 (0.70) | PRSS1TPSAB1F2 | |
| SCHEMBL20817059 | 1.00 | PRSS1 (0.70) | PRSS1TPSAB1F2 | |
| Sulfuric Acid SCHEMBL5045181 | 0.98 | PRSS1 (0.67) | PRSS1TPSAB1F2 | |
| Nitric Acid SCHEMBL5634370 | 0.95 | PRSS1 (0.78) | PRSS1TPSAB1F2 | |
| Nitric Acid SCHEMBL5634066 | 0.95 | PRSS1 (0.78) | PRSS1TPSAB1F2 | |
| Nitric Acid SCHEMBL5040734 | 0.95 | PRSS1 (0.78) | PRSS1TPSAB1F2 | |
| SCHEMBL14524837 | 0.91 | PRSS1 (0.65) | PRSS1TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205384-B2 | Process for preparing peptidyl heterocyclic ketone derivatives | ORTHO-MCNEIL PHARMACEUTICAL INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205384-B2 | Process for preparing peptidyl heterocyclic ketone derivatives | ORTHO-MCNEIL PHARMACEUTICAL INC. (US) | 2007-04-17 | — | — | US | disclosed |
| WO-2005023804-A1 | PEPTIDYL HETEROCYCLIC KETONE DERIVATIVES AND PREPARATION PROCESSES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-17 | — | — | WO | disclosed |