Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952997 | 0.85 | ALDH1A1 (0.55) | KMT2AMEN1ATMAVPR1AALDH1A1 | |
| SCHEMBL3428161 | 0.83 | DPP4 (0.61) | CYP3A4DPP4KMT2AMEN1ATM | |
| SCHEMBL8306239 | 0.76 | DPP4 (0.71) | CYP3A4DPP4 | |
| SCHEMBL8302314 | 0.75 | DPP4 (0.79) | CYP3A4DPP4 | |
| SCHEMBL31240990 | 0.75 | CACNA2D1 (0.47) | KMT2AMEN1ATMAVPR1ACYP1A2 | |
| SCHEMBL27074582 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1HDAC1CYP1A2 | |
| SCHEMBL30757987 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1HDAC1CYP1A2 | |
| SCHEMBL9954421 | 0.71 | MEN1 (0.51) | KMT2AMEN1ATMAVPR1AALDH1A1 | |
| SCHEMBL6797484 | 0.71 | POLB (0.72) | KMT2AMEN1ATMALDH1A1CYP1A2 | |
| SCHEMBL3425757 | 0.71 | CYP3A4 (0.63) | CYP3A4DPP4KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087053-A9 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX INC (US) | 2004-11-11 | — | — | WO | disclosed |
| WO-2004087053-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX, INC. (US) | 2004-10-14 | — | — | WO | disclosed |