Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.64 |
| ▸ | CSF1R | P07333 | 12/20 | 0.64 |
| ▸ | LCK | P06239 | 3/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | KIF5B | P33176 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAF1 | P04049 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181700 | 0.78 | EGFR (1.00) | EGFRCSF1RLCKPDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL6180093 | 0.78 | EGFR (1.00) | EGFRCSF1RLCKPDGFRBPDGFRA | |
| SCHEMBL6184794 | 0.76 | EGFR (0.76) | EGFRCSF1RLCKPDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL6181502 | 0.75 | EGFR (0.77) | EGFRCSF1RLCKPDGFRBPDGFRA | |
| SCHEMBL2257706 | 0.74 | CSF1R (1.00) | EGFRCSF1RPDGFRBPDGFRARET | |
| Hydrochloric Acid SCHEMBL6179746 | 0.73 | CSF1R (1.00) | EGFRCSF1RPDGFRBPDGFRARET | |
| SCHEMBL8177845 | 0.71 | EGFR (1.00) | EGFRCSF1RPDGFRBPDGFRARET | |
| Hydrochloric Acid SCHEMBL6181342 | 0.70 | EGFR (1.00) | EGFRCSF1RLCKPDGFRBPDGFRA | |
| SCHEMBL6180768 | 0.69 | CSF1R (1.00) | EGFRCSF1RPDGFRBPDGFRARET | |
| SCHEMBL6181964 | 0.69 | EGFR (0.77) | EGFRCSF1RLCKPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | claimed |