Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471442 | 0.88 | HTR1A (0.52) | KMT2AMEN1HTTGAAHTR1A | |
| SCHEMBL1471320 | 0.86 | KMT2A (0.57) | KMT2AMEN1HTTGAAHTR1A | |
| SCHEMBL8307159 | 0.85 | MEN1 (0.52) | KMT2AMEN1HTTGAAHTR1A | |
| SCHEMBL1471024 | 0.84 | HTR1A (0.53) | KMT2AMEN1HTTGAAHTR1A | |
| SCHEMBL1470908 | 0.84 | HTR1A (0.42) | KMT2AMEN1HTTGAAHTR1A | |
| SCHEMBL1470736 | 0.81 | NPC1 (0.41) | KMT2AMEN1HTTHTR1ADRD2 | |
| SCHEMBL1471026 | 0.81 | HTR1A (0.53) | KMT2AMEN1HTTGAAHTR1A | |
| SCHEMBL1471446 | 0.80 | HDAC1 (0.41) | KMT2AMEN1HTTHTR1ADRD2 | |
| SCHEMBL1471053 | 0.79 | KMT2A (0.60) | KMT2AMEN1HTTGAAHTR1A | |
| SCHEMBL1470751 | 0.78 | SMN1; SMN2 (0.42) | KMT2AMEN1HTTGAAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021525-A1 | ARYL PIPERIDINE AMIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-10 | — | — | WO | disclosed |