Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305663 | 0.82 | CHRM2 (0.39) | ALDH1A1MAPTMEN1KMT2ACHRM2 | |
| SCHEMBL8304898 | 0.82 | CHRM2 (0.39) | ALDH1A1MAPTMEN1KMT2ACHRM2 | |
| SCHEMBL16032150 | 0.79 | HPGD (0.47) | ALDH1A1MAPTLMNAHPGDRECQL | |
| SCHEMBL16032152 | 0.79 | HPGD (0.47) | ALDH1A1MAPTLMNAHPGDRECQL | |
| SCHEMBL16794418 | 0.74 | HSD17B10 (0.44) | ALDH1A1MAPTMEN1KMT2ACHRM2 | |
| SCHEMBL8307167 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL31209483 | 0.73 | HPGD (0.48) | ALDH1A1MAPTMEN1KMT2ACHRM2 | |
| SCHEMBL14803835 | 0.72 | MEN1 (0.49) | ALDH1A1MAPTMEN1KMT2ACHRM2 | |
| SCHEMBL30984312 | 0.72 | MEN1 (0.49) | ALDH1A1MAPTMEN1KMT2ACHRM2 | |
| SCHEMBL5426179 | 0.72 | NR1H2 (0.56) | ALDH1A1MAPTMEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646116-B1 | PROCESS AND INTERMEDIATES FOR BIS-AZA-BICYCLIC ANXIOLYTIC AGENTS | PFIZER (US) | 1999-10-13 | — | — | EP | claimed |