Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.46 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308405 | 0.89 | CNR1 (0.53) | CNR1CNR2HTTTTBK1TTBK2 | |
| SCHEMBL15684755 | 0.83 | HTT (0.49) | CNR1CNR2HTTTTBK1TTBK2 | |
| SCHEMBL15684987 | 0.83 | RAB9A (0.60) | HTTTTBK1TTBK2MEN1LMNA | |
| SCHEMBL9039173 | 0.82 | CNR1 (0.48) | CNR1CNR2HTTTTBK1TTBK2 | |
| SCHEMBL9039992 | 0.82 | CNR1 (0.48) | CNR1CNR2HTTTTBK1TTBK2 | |
| SCHEMBL8303441 | 0.80 | HTT (0.47) | HTTTTBK1TTBK2MEN1LMNA | |
| SCHEMBL8307878 | 0.80 | HTT (0.54) | CNR1CNR2HTTLMNATSHR | |
| SCHEMBL8303763 | 0.79 | GALR3 (0.46) | HTTTTBK1TTBK2MEN1LMNA | |
| SCHEMBL9085869 | 0.78 | GALR3 (0.45) | CNR1HTTTTBK1TTBK2MEN1 | |
| SCHEMBL17133553 | 0.77 | PDE2A (0.47) | CNR1HTTTTBK1TTBK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555388-B1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | DU PONT (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5378708-A | Agricultural pesticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1992008704-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |