Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098492 | 1.00 | DRD4 (0.36) | DRD4CCR3OPRM1OPRL1CCR1 | |
| SCHEMBL6098489 | 1.00 | DRD4 (0.36) | DRD4CCR3OPRM1OPRL1CCR1 | |
| SCHEMBL8312834 | 0.85 | CCR5 (0.40) | DRD4CCR3OPRM1OPRL1CCR1 | |
| SCHEMBL6096743 | 0.85 | CCR5 (0.40) | DRD4CCR3OPRM1OPRL1CCR1 | |
| SCHEMBL6096740 | 0.85 | CCR5 (0.40) | DRD4CCR3OPRM1OPRL1CCR1 | |
| SCHEMBL6274732 | 0.85 | CCR3 (0.34) | CCR3CCR1ALDH1A1 | |
| SCHEMBL6841776 | 0.84 | BCHE (0.33) | CCR3OPRM1OPRL1CCR1 | |
| SCHEMBL6095673 | 0.81 | CCR1 (0.39) | CCR1ALDH1A1 | |
| SCHEMBL6095667 | 0.81 | CCR1 (0.39) | CCR1ALDH1A1 | |
| SCHEMBL6095902 | 0.80 | CCR1 (0.38) | OPRM1CCR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080460-A1 | SUBSTITUTED PIPERIDINES AS NOVEL MDM2-p53 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-23 | — | — | WO | disclosed |