Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | FNTA | P49354 | 3/20 | 0.50 |
| ▸ | FNTB | P49356 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306433 | 1.00 | KMT2A (0.52) | KMT2AOPRK1ALDH1A1KDM4EFNTA | |
| SCHEMBL8159389 | 0.85 | FNTA (0.53) | OPRK1ALDH1A1FNTAFNTB | |
| SCHEMBL8159392 | 0.85 | FNTA (0.53) | OPRK1ALDH1A1FNTAFNTB | |
| SCHEMBL4600047 | 0.83 | CHRM2 (0.52) | KMT2AOPRK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL4600052 | 0.83 | CHRM2 (0.52) | KMT2AOPRK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8439130 | 0.82 | FNTA (0.63) | KMT2AALDH1A1FNTAFNTBMEN1 | |
| SCHEMBL7751346 | 0.82 | FNTA (0.63) | KMT2AALDH1A1FNTAFNTBMEN1 | |
| SCHEMBL8307524 | 0.82 | FNTA (0.58) | ALDH1A1FNTAFNTB | |
| SCHEMBL8307525 | 0.82 | FNTA (0.58) | ALDH1A1FNTAFNTB | |
| SCHEMBL8302399 | 0.81 | FNTA (0.49) | ALDH1A1FNTAFNTBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952842-A2 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-11-03 | — | — | EP | disclosed |
| WO-1997038664-A2 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | disclosed |