Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.58 |
| ▸ | FNTB | P49356 | 9/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307525 | 1.00 | FNTA (0.58) | FNTAFNTBLTA4HANPEPPGGT1B | |
| SCHEMBL8306507 | 0.89 | OPRK1 (0.58) | FNTAFNTBANPEP | |
| SCHEMBL8306505 | 0.89 | OPRK1 (0.58) | FNTAFNTBANPEP | |
| SCHEMBL8792533 | 0.86 | MEN1 (0.52) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL8792528 | 0.86 | MEN1 (0.52) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL8159392 | 0.85 | FNTA (0.53) | FNTAFNTBLTA4HNPSR1ALDH1A1 | |
| SCHEMBL8159389 | 0.85 | FNTA (0.53) | FNTAFNTBLTA4HNPSR1ALDH1A1 | |
| SCHEMBL2331099 | 0.83 | FNTA (0.61) | FNTAFNTBLTA4HANPEPPGGT1B | |
| SCHEMBL2331097 | 0.83 | FNTA (0.61) | FNTAFNTBLTA4HANPEPPGGT1B | |
| SCHEMBL27639931 | 0.83 | LTA4H (0.55) | FNTAFNTBLTA4HANPEPPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952842-A2 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-11-03 | — | — | EP | claimed |
| WO-1997038664-A2 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | claimed |