Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1885829 | 0.94 | ACE2 (0.50) | ACE2CXCR4HSD17B10CA12CA6 | |
| SCHEMBL15065607 | 0.92 | CXCR4 (0.54) | ACE2CXCR4HSD17B10ANPEPERAP2 | |
| SCHEMBL26522670 | 0.90 | ACE2 (0.67) | ACE2CXCR4HSD17B10CA12CA6 | |
| Norspermidine SCHEMBL28830161 | 0.90 | ACE2 (0.50) | ACE2CXCR4HSD17B10CA12CA6 | |
| SCHEMBL11580070 | 0.90 | ACE2 (0.59) | ACE2CXCR4HSD17B10CA12CA6 | |
| SCHEMBL302850 | 0.90 | ACE2 (0.72) | ACE2CXCR4HSD17B10CA12CA6 | |
| Trientine SCHEMBL10749311 | 0.88 | ACE2 (0.57) | ACE2CXCR4HSD17B10CA12CA6 | |
| SCHEMBL600834 | 0.88 | ACE2 (0.69) | ACE2CXCR4HSD17B10CA12CA6 | |
| SCHEMBL4388203 | 0.88 | ACE2 (0.57) | ACE2CXCR4HSD17B10CA12CA6 | |
| Trientine SCHEMBL9064137 | 0.88 | ACE2 (0.69) | ACE2CXCR4HSD17B10CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |