SCHEMBL1885829

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Norspermidine SCHEMBL28830161	0.96	ACE2 (0.50)	ACE2CXCR4CASP2CA12F13A1
	SCHEMBL8306593	0.94	ACE2 (0.57)	ACE2CXCR4CA12CA2ALOX15
	SCHEMBL5498811	0.92	ACE2 (0.61)	ACE2CXCR4CASP2CA12F13A1
	SCHEMBL15065607	0.90	CXCR4 (0.54)	ACE2CXCR4ALOX15HSD17B10MEN1
	SCHEMBL26398569	0.86	ACE2 (0.67)	ACE2CASP2CA12F13A1CA2
	SCHEMBL26522670	0.85	ACE2 (0.67)	ACE2CXCR4CA12CA2ALOX15
	SCHEMBL11580070	0.84	ACE2 (0.59)	ACE2CXCR4CA12CA2ALOX15
	SCHEMBL302850	0.84	ACE2 (0.72)	ACE2CXCR4CA12CA2ALOX15
	SCHEMBL15065509	0.84	CXCR4 (0.55)	ACE2CXCR4ALOX15HSD17B10TSHR
	SCHEMBL6961878	0.83	CXCR4 (0.56)	ACE2CXCR4ALOX15HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.