Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26128039 | 0.84 | CA12 (0.48) | CA12CA9IDO1HSD17B10KDM4E | |
| SCHEMBL30366037 | 0.79 | HSD17B3 (0.40) | SMN1; SMN2MAPTCA12CA9HSD17B3 | |
| SCHEMBL28390255 | 0.79 | HSD17B3 (0.40) | SMN1; SMN2MAPTCA12CA9HSD17B3 | |
| SCHEMBL980578 | 0.77 | MAOA (0.35) | RAB9AMAPTHSD17B3BRPF1MAOB | |
| SCHEMBL29816130 | 0.77 | MAOA (0.35) | RAB9AMAPTHSD17B3BRPF1MAOB | |
| SCHEMBL27868242 | 0.76 | TSHR (0.46) | MAPTCA12CA9IDO1HSD17B10 | |
| SCHEMBL715561 | 0.76 | HSD17B10 (0.33) | MAPTHSD17B3BRPF1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL27489771 | 0.76 | BLM (0.34) | MAPTHSD17B3BRPF1MAOBHSD17B10 | |
| SCHEMBL27719045 | 0.76 | HSD17B3 (0.33) | RAB9ASMN1; SMN2MAPTNPC1NFKB1 | |
| Hydrochloric Acid SCHEMBL3719374 | 0.76 | BLM (0.34) | MAPTHSD17B3BRPF1MAOBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633261-B1 | QUINOLINE-3-ACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | YOSHITOMI PHARMACEUTICAL (JP) | 1999-04-21 | — | — | EP | disclosed |
| US-5543420-A | ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AGENTS; PREVENTION OF ACCUMULATION OF SORBITOL AND GALACTITOL IN MAMMALIAN TISSUE | THE GREEN CROSS CORPORATION (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0633261-A1 | QUINOLINE-3-ACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1995-01-11 | — | — | EP | disclosed |