Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838007 | 0.89 | PTGS2 (0.42) | PTGS2PRKCIGAALMNASMN1; SMN2 | |
| SCHEMBL2838102 | 0.88 | PTGS2 (0.41) | PTGS2PRKCIGAALMNASMN1; SMN2 | |
| SCHEMBL2839485 | 0.88 | PTGS2 (0.41) | PTGS2PRKCIGAALMNASMN1; SMN2 | |
| SCHEMBL2839668 | 0.87 | PTGS2 (0.43) | PTGS2PRKCIGAALMNASMN1; SMN2 | |
| SCHEMBL2838725 | 0.87 | PTGS2 (0.41) | PTGS2PRKCIGAALMNASMN1; SMN2 | |
| SCHEMBL2833583 | 0.86 | PRKCI (0.40) | PTGS2PRKCIGAALMNASMN1; SMN2 | |
| SCHEMBL2836374 | 0.86 | KDM4E (0.41) | PTGS2PRKCIGAALMNASMN1; SMN2 | |
| SCHEMBL2838042 | 0.84 | PTGS2 (0.43) | PTGS2GAALMNASMN1; SMN2MAPK1 | |
| SCHEMBL2843019 | 0.84 | KDM4E (0.40) | PTGS2PRKCIGAALMNASMN1; SMN2 | |
| SCHEMBL14493329 | 0.84 | KDM4E (0.40) | PTGS2PRKCIGAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065391-A1 | 4-AMINOTHIENO[2,3-d]PYRIMIDINE-6-CARBONITRILE DERIVATIVES AS PDE7 INHIBITORS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-08-05 | — | — | WO | disclosed |