Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.73 |
| ▸ | MAOA | P21397 | 3/20 | 0.73 |
| ▸ | F10 | P00742 | 6/20 | 0.66 |
| ▸ | CALML3 | P27482 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | SDHA | P31040 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306792 | 1.00 | MAOB (0.73) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL18396775 | 0.96 | MAOB (0.68) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL18396777 | 0.96 | MAOB (0.68) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL8305130 | 0.93 | MAOB (0.64) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL18396744 | 0.93 | MAOB (0.64) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL18396747 | 0.93 | MAOB (0.64) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL8305126 | 0.93 | MAOB (0.64) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL28109794 | 0.90 | CALML3 (0.65) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL77866 | 0.89 | MAOB (0.70) | MAOBMAOAF10CALML3LMNA | |
| SCHEMBL3519368 | 0.89 | MAOB (0.70) | MAOBMAOAF10CALML3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717738-B1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5880118-A | Substituted oxazine and thiazine oxazolidinone antimicrobials | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| US-5688792-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-18 | — | — | US | disclosed |