Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305168 | 0.88 | TBXAS1 (0.78) | TBXAS1 | |
| SCHEMBL8304728 | 0.87 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8309257 | 0.87 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8304831 | 0.85 | TBXAS1 (0.74) | TBXAS1 | |
| SCHEMBL8304834 | 0.84 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8309213 | 0.84 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8306901 | 0.83 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8310769 | 0.82 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8305166 | 0.81 | TBXAS1 (0.81) | TBXAS1 | |
| SCHEMBL8308584 | 0.81 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579618-B1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1999-10-13 | — | — | EP | disclosed |
| US-5457118-A | Pyridine derived agents for cardiovascular diseases | PFIZER INC. (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0579618-A1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | Pfizer Limited (GB) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992017451-A1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | PFIZER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |