Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311286 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL8306834 | 0.89 | KDM4E (0.55) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL8312062 | 0.88 | KDM4E (0.61) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL8312543 | 0.88 | KDM4E (0.77) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2840498 | 0.88 | ALDH1A1 (0.76) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2833135 | 0.87 | ALDH1A1 (0.74) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2837251 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL8311877 | 0.86 | KDM4E (0.58) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2834062 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2835325 | 0.85 | KDM4E (0.62) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065391-A1 | 4-AMINOTHIENO[2,3-d]PYRIMIDINE-6-CARBONITRILE DERIVATIVES AS PDE7 INHIBITORS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-08-05 | — | — | WO | disclosed |