SCHEMBL8306880

SCHEMBL8306880

Fc1ccc(OCc2cccc(Br)c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 15/20 0.71
PARP15 Q460N3 3/20 0.61
PARP10 Q53GL7 3/20 0.61
PARP14 Q460N5 1/20 0.61
FFAR1 O14842 1/20 0.58
FFAR4 Q5NUL3 1/20 0.58
MAOA P21397 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16795673 0.86 MAOB (0.69) MAOBPARP15PARP10PARP14FFAR1
SCHEMBL16795545 0.85 MAOB (0.88) MAOBPARP15PARP10MAOA
SCHEMBL13469158 0.84 MAOB (0.82) MAOBPARP15PARP10PARP14FFAR1
SCHEMBL27521276 0.84 MAOB (0.77) MAOBPARP10MAOA
SCHEMBL23004576 0.83 MAOB (0.69) MAOBPARP15PARP10PARP14FFAR1
SCHEMBL16795567 0.83 MAOB (0.79) MAOBPARP15PARP10PARP14FFAR1
SCHEMBL30398538 0.83 MAOB (0.69) MAOBPARP15PARP10PARP14FFAR1
SCHEMBL16795800 0.83 MAOB (0.69) MAOBPARP15PARP10PARP14FFAR1
SCHEMBL3321461 0.83 MAOB (0.69) MAOBPARP15PARP10PARP14FFAR1
SCHEMBL15156306 0.83 MAOB (0.73) MAOBPARP10MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015087094-A1 NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES SEMMELWEIS EGYETEM (HU) 2015-06-18 WO disclosed
WO-2005019200-A2 ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF ICOS CORPORATION (US) 2005-03-03 WO disclosed