Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.69 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795545 | 0.88 | MAOB (0.88) | MAOBMAOAPARP15PARP10MRGPRX4 | |
| SCHEMBL8306880 | 0.86 | MAOB (0.71) | MAOBMAOAPARP15PARP10PARP14 | |
| SCHEMBL4426765 | 0.84 | MAOB (0.67) | MAOBMAOAPARP10IDO1AGXT | |
| SCHEMBL4404036 | 0.82 | MAOB (1.00) | MAOBMAOAPARP15PARP10PARP14 | |
| SCHEMBL16795515 | 0.81 | MAOB (1.00) | MAOBMAOAMRGPRX4 | |
| SCHEMBL13469158 | 0.80 | MAOB (0.82) | MAOBMAOAPARP15PARP10PARP14 | |
| SCHEMBL5042093 | 0.80 | ALOX5 (0.55) | MAOBMAOAFFAR1 | |
| SCHEMBL2226602 | 0.79 | MAOB (0.62) | MAOBMAOAFFAR1 | |
| SCHEMBL16808938 | 0.79 | MAOB (0.61) | MAOBMAOAIDO1MRGPRX4 | |
| SCHEMBL12327547 | 0.79 | MAOB (0.51) | MAOBMAOAPARP10MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087094-A1 | NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SEMMELWEIS EGYETEM (HU) | 2015-06-18 | — | — | WO | disclosed |