Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706798 | 0.68 | CHRM3 (0.39) | CHRM3KDM4EHPGDLMNACHRM2 | |
| SCHEMBL17706800 | 0.68 | CHRM3 (0.39) | CHRM3KDM4EHPGDLMNACHRM2 | |
| SCHEMBL6960679 | 0.67 | CHRM3 (0.53) | CHRM3KDM4EHPGDLMNACHRM2 | |
| SCHEMBL27944568 | 0.66 | — | — | |
| SCHEMBL17775379 | 0.66 | CHRM3 (0.37) | CHRM3KDM4EHPGDLMNACHRM2 | |
| Hydrochloric Acid SCHEMBL7082979 | 0.66 | CHRM3 (0.51) | CHRM3KDM4EHPGDLMNACHRM2 | |
| SCHEMBL20161452 | 0.65 | FUCA1 (0.39) | KDM4EHPGDLMNANPC1MAPK1 | |
| SCHEMBL8588994 | 0.65 | — | — | |
| SCHEMBL21891254 | 0.65 | CHRM3 (0.46) | CHRM3KDM4EHPGDLMNACHRM2 | |
| Hydrochloric Acid SCHEMBL8587102 | 0.64 | CHRM3 (0.42) | CHRM3KDM4EHPGDLMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630244-B1 | MUSCARINIC AGONISTS | UNIV TOLEDO (US) | 1999-12-01 | — | — | EP | claimed |
| EP-0630244-A4 | MUSCARINIC AGONISTS. | UNIV TOLEDO (US) | 1994-04-07 | — | — | EP | claimed |
| EP-0630244-A4 | MUSCARINIC AGONISTS. | UNIV TOLEDO (US) | 1994-04-07 | — | — | EP | disclosed |