SCHEMBL8588994

SCHEMBL8588994

COC(=O)C1=CC(C)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19275006 0.81 ALDH1A1 (0.39)
SCHEMBL10478110 0.77 LMNA (0.44)
SCHEMBL6538254 0.77 CHRM3 (0.38)
(-)-Methyl Shikimate SCHEMBL15983807 0.77 ALDH1A1 (0.36)
SCHEMBL15983808 0.75 ALDH1A1 (0.35)
SCHEMBL15983812 0.74 MAPT (0.35)
SCHEMBL15929789 0.74 CHRM3 (0.37)
SCHEMBL15929795 0.74 SLC6A3 (0.33)
SCHEMBL11313805 0.74 CHRM3 (0.36)
SCHEMBL1716907 0.74 CHRM3 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5795567-A HYDROFORMYLATION FOLLOWED BY REDUCTIVE AMINATION AND ATTACHING A CHLOROORGANOSILYL COMPOUND; DRUG DELIVERTYSYSTEMS MONSANTO COMPANY (US) 1998-08-18 US disclosed
US-5693319-A HYDROFORMYLATING OLEFINIC-CONTAINING POLYMER IN PRESENCE OF CATALYST, REDUCTIVELY AMINATING MONSANTO COMPANY (US) 1997-12-02 US disclosed
US-5676939-A CROSSLINKING; CONTROLLING DENSITY; DRUG DELIVERY MONSANTO COMPANY (US) 1997-10-14 US disclosed
EP-0502839-B1 Functionalized polymers MONSANTO CO (US) 1997-07-09 EP disclosed
EP-0540670-B1 METHOD FOR PREPARATION OF CROSSLINKED POLYAMINES MONSANTO CO (US) 1996-03-20 EP disclosed
US-5474767-A Crosslinked; controlled density; water insoluble; residual unsaturation MONSANTO COMPANY (US) 1995-12-12 US disclosed
US-5294675-A A-C copoly;hydroformylation MONSANTO COMPANY (US) 1994-03-15 US disclosed
US-5232989-A Hydroformylation of polyoefins, reduction to hydroxyl groups, reacting with diisocyanate MONSANTO COMPANY (US) 1993-08-03 US disclosed
EP-0540670-A1 NOVEL POLYAMINES AND METHOD FOR PREPARATION THEREOF. MONSANTO CO (US) 1993-05-12 EP disclosed
EP-0502839-A2 Functionalized polymers MONSANTO COMPANY (US) 1992-09-09 EP disclosed
WO-1992001730-A1 NOVEL POLYAMINES AND METHOD FOR PREPARATION THEREOF MONSANTO COMPANY (US) 1992-02-06 WO disclosed