⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307135 | 0.76 | TRPV4 (0.35) | — | |
| SCHEMBL790743 | 0.70 | — | — | |
| SCHEMBL193055 | 0.69 | — | — | |
| SCHEMBL10505078 | 0.65 | — | — | |
| SCHEMBL8306651 | 0.65 | HSP90AA1 (0.31) | — | |
| SCHEMBL9361857 | 0.65 | HPGD (0.36) | — | |
| SCHEMBL1672572 | 0.62 | — | — | |
| SCHEMBL10675525 | 0.61 | — | — | |
| SCHEMBL8309613 | 0.61 | TRPV4 (0.34) | — | |
| SCHEMBL5799987 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576251-B1 | Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment | SUNTORY LTD (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-5424310-A | Substituted 1,2,4-triazine-3,5-dione derivative and anticoccidial drug composition containing the same as active component | SUNTORY LIMITED (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0576251-A1 | Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment | SUNTORY LIMITED (JP) | 1993-12-29 | — | — | EP | disclosed |