Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | SDHA | P31040 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CALML3 | P27482 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304945 | 0.91 | MAOB (0.70) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8307496 | 0.90 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL21968386 | 0.87 | MAOA (0.68) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7490047 | 0.84 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6616017 | 0.83 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6616021 | 0.83 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8308401 | 0.83 | MAOA (0.76) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8308403 | 0.83 | MAOA (0.76) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6628230 | 0.82 | MAOA (0.54) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7484787 | 0.82 | MAOB (0.78) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730591-B1 | ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES | UPJOHN CO (US) | 1999-07-14 | — | — | EP | claimed |