Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310662 | 0.98 | ACE2 (0.64) | ACE2HRH3SCN5ACA12CA6 | |
| SCHEMBL15295964 | 0.94 | ACE2 (0.54) | ACE2HRH3SCN5ACA12CA6 | |
| SCHEMBL4361290 | 0.94 | ACE2 (0.54) | ACE2HRH3SCN5ACA12CA6 | |
| SCHEMBL6510779 | 0.94 | ACE2 (0.54) | ACE2HRH3SCN5ACA12CA6 | |
| SCHEMBL6506342 | 0.94 | ACE2 (0.54) | ACE2HRH3SCN5ACA12CA6 | |
| SCHEMBL22899785 | 0.93 | ACE2 (0.64) | ACE2HRH3SCN5ACA12CA6 | |
| SCHEMBL10939162 | 0.91 | ACE2 (0.56) | ACE2HRH3SCN5ACA12CA6 | |
| SCHEMBL5911217 | 0.91 | HRH3 (0.62) | ACE2HRH3SCN5ACA12CA9 | |
| SCHEMBL10904240 | 0.89 | ACE2 (0.78) | ACE2HRH3CA12CA6CA7 | |
| SCHEMBL239132 | 0.89 | ACE2 (0.78) | ACE2HRH3CA12CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |