Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MB | P02144 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198479 | 0.87 | ALDH1A1 (0.58) | POLBSMN1; SMN2ALDH1A1TP53HIF1A | |
| SCHEMBL11235452 | 0.85 | POLB (1.00) | POLBSMN1; SMN2ALDH1A1TP53HIF1A | |
| SCHEMBL31661220 | 0.84 | ALDH1A1 (0.63) | POLBSMN1; SMN2ALDH1A1TP53HIF1A | |
| SCHEMBL11439273 | 0.84 | ALDH1A1 (0.58) | POLBSMN1; SMN2ALDH1A1TP53HIF1A | |
| SCHEMBL8591572 | 0.83 | POLB (0.77) | POLBSMN1; SMN2ALDH1A1PKMKMT2A | |
| SCHEMBL8308427 | 0.81 | POLB (0.70) | POLBSMN1; SMN2ALDH1A1PKMKMT2A | |
| SCHEMBL31254026 | 0.81 | SMN1; SMN2 (0.72) | POLBSMN1; SMN2ALDH1A1TP53PKM | |
| SCHEMBL1258654 | 0.81 | SMN1; SMN2 (0.72) | POLBSMN1; SMN2ALDH1A1TP53PKM | |
| SCHEMBL2492405 | 0.80 | TDP1 (0.55) | POLBSMN1; SMN2ALDH1A1TP53HIF1A | |
| SCHEMBL6105675 | 0.80 | ALDH1A1 (0.54) | POLBSMN1; SMN2ALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295103-A1 | AURONE DERIVATIVES AND USES THEREOF FOR CONTROLLING BACTERIA AND/OR FUNGI | ECOLE CENTRALE DE MARSEILLE (FR) | 2023-09-21 | — | — | US | disclosed |
| US-20230295103-A1 | AURONE DERIVATIVES AND USES THEREOF FOR CONTROLLING BACTERIA AND/OR FUNGI | ECOLE CENTRALE DE MARSEILLE (FR) | 2023-09-21 | — | — | US | disclosed |
| WO-2022008678-A2 | AURONE DERIVATIVES AND USES THEREOF FOR CONTROLLING BACTERIA AND/OR FUNGI | UNIVERSITE D'AIX-MARSEILLE (FR) | 2022-01-13 | — | — | WO | disclosed |
| EP-0685475-B1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1999-01-13 | — | — | EP | disclosed |
| US-5622989-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0685475-A1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295103-A1 | AURONE DERIVATIVES AND USES THEREOF FOR CONTROLLING BACTERIA AND/OR FUNGI | AURKA, CYP51A1, AURKC | POLB 2048/4885SMN1; SMN2 4857/4885ALDH1A1 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.