Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307395 | 1.00 | KMT2A (0.57) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL8307399 | 1.00 | KMT2A (0.57) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL7245547 | 0.84 | KMT2A (0.51) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL4800296 | 0.83 | FFAR2 (0.52) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL10024197 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL10024369 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL10024368 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL10024198 | 0.82 | KMT2A (0.52) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL10024366 | 0.81 | KMT2A (0.66) | KMT2AALDH1A1MEN1POLBMMP2 | |
| SCHEMBL10024367 | 0.81 | KMT2A (0.66) | KMT2AALDH1A1MEN1POLBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| US-5700817-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD. (KR) | 1997-12-23 | — | — | US | disclosed |
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |