Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307508 | 1.00 | KDM4E (0.33) | KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL8175954 | 1.00 | KDM4E (0.33) | KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL8185887 | 1.00 | KDM4E (0.33) | KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL8175953 | 1.00 | KDM4E (0.33) | KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL8185890 | 1.00 | KDM4E (0.33) | KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL7994401 | 0.98 | ALDH1A1 (0.32) | KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL8119123 | 0.98 | ALDH1A1 (0.32) | KDM4ETDP1ALDH1A1ALOX15 | |
| SCHEMBL7980424 | 0.91 | — | — | |
| SCHEMBL8186498 | 0.86 | CHRM5 (0.30) | — | |
| SCHEMBL8186502 | 0.86 | CHRM5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |