Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 17/20 | 0.51 |
| ▸ | HAT1 | O14929 | 2/20 | 0.47 |
| ▸ | EP300 | Q09472 | 2/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396280 | 0.84 | F10 (0.57) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL21824244 | 0.83 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL2804991 | 0.81 | NPC1 (0.62) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL30166600 | 0.81 | HDAC8 (0.44) | PDE4APDE4BPDE4CPDE4DHAT1 | |
| SCHEMBL30166619 | 0.80 | SPR (0.59) | F10PLATKLKB1 | |
| SCHEMBL2001808 | 0.80 | SPR (0.59) | F10PLATKLKB1 | |
| SCHEMBL4693749 | 0.80 | F10 (0.46) | PDE4APDE4BPDE4CPDE4DF10 | |
| SCHEMBL8289917 | 0.79 | MEN1 (0.48) | PDE4APDE4BPDE4CPDE4DF10 | |
| Hydrochloric Acid SCHEMBL30166603 | 0.79 | F10 (0.55) | F10PLATKLKB1 | |
| SCHEMBL4403020 | 0.78 | F10 (0.46) | PDE4APDE4BPDE4CPDE4DF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650985-B | Heterocyclic compounds as RET kinase inhibitors | 癌症研究科技有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-115650985-A | Heterocyclic compounds as RET kinase inhibitors | 癌症研究科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-109195972-B | Heterocyclic compounds as RET kinase inhibitors | 癌症研究科技有限公司 | 2022-10-28 | — | — | CN | disclosed |
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |