SCHEMBL8307541

SCHEMBL8307541

CCn1ncc(C(=O)c2ccc3c(c2C)C(OC)CCS3(=O)=O)c1OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8940922 0.94 NPC1 (0.30) SMN1; SMN2
SCHEMBL8613647 0.92 F2 (0.32)
SCHEMBL8940932 0.89 ALDH1A1 (0.30) ALDH1A1GAAHTTSMN1; SMN2
SCHEMBL8301862 0.89
SCHEMBL8303291 0.88 ALDH1A1 (0.31) ALDH1A1GAAHTTSMN1; SMN2
SCHEMBL8308195 0.86 ALDH1A1 (0.30) ALDH1A1
SCHEMBL8940979 0.86 NPC1 (0.30) SMN1; SMN2
SCHEMBL8618473 0.84
SCHEMBL9039136 0.83
SCHEMBL8128911 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0629623-B1 PYRAZOLE DERIVATIVE IDEMITSU KOSAN CO (JP) 1999-05-19 EP disclosed
US-5587484-A HALOGENATION; OXIDATION; SULFONATION; HERBICIDES IDEMITSU KOSAN CO., LTD. (JP) 1996-12-24 US disclosed
US-5468722-A Herbicides for corn, wheat, barley IDEMITSU KOSAN CO., LTD. (JP) 1995-11-21 US disclosed
EP-0629623-A1 PYRAZOLE DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-12-21 EP disclosed