Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | F2 | P00734 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312634 | 0.93 | TP53 (0.68) | ALDH1A1F2HSD17B10KMT2ALMNA | |
| SCHEMBL8312202 | 0.92 | TP53 (0.70) | ALDH1A1F2HSD17B10KMT2ALMNA | |
| SCHEMBL8308860 | 0.92 | TP53 (0.70) | ALDH1A1F2HSD17B10KMT2ALMNA | |
| SCHEMBL8311201 | 0.87 | HSD17B10 (0.66) | ALDH1A1F2HSD17B10KMT2ALMNA | |
| SCHEMBL8303967 | 0.85 | TP53 (0.58) | ALDH1A1F2HSD17B10KMT2ALMNA | |
| SCHEMBL8306952 | 0.83 | KDM4E (0.62) | ALDH1A1F2HSD17B10LMNAHPGD | |
| SCHEMBL8306903 | 0.80 | KDM4E (0.74) | ALDH1A1KMT2AHPGDMEN1KDM4E | |
| SCHEMBL8306279 | 0.79 | TP53 (0.75) | ALDH1A1LMNAKDM4ETP53BACE1 | |
| SCHEMBL8312500 | 0.79 | TP53 (0.78) | ALDH1A1LMNAKDM4ETP53BACE1 | |
| SCHEMBL8308783 | 0.78 | TP53 (0.75) | ALDH1A1KMT2ALMNAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |