Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308161 | 0.92 | LMNA (0.68) | KDM4EBACE1ALDH1A1RXFP1HTT | |
| SCHEMBL8311830 | 0.91 | MAPT (0.68) | KDM4EBACE1ALDH1A1RXFP1HTT | |
| SCHEMBL8311201 | 0.88 | HSD17B10 (0.66) | KDM4EBACE1ALDH1A1RXFP1HTT | |
| SCHEMBL8305689 | 0.88 | LMNA (0.69) | KDM4EBACE1ALDH1A1RXFP1HTT | |
| SCHEMBL8307633 | 0.83 | ALDH1A1 (0.78) | KDM4EBACE1ALDH1A1HTTLMNA | |
| SCHEMBL8307086 | 0.82 | MAPT (0.71) | BACE1ALDH1A1RXFP1HTTLMNA | |
| SCHEMBL8306903 | 0.81 | KDM4E (0.74) | KDM4EBACE1ALDH1A1RXFP1MAPT | |
| SCHEMBL8304661 | 0.81 | RXFP1 (0.67) | KDM4EBACE1ALDH1A1RXFP1HTT | |
| SCHEMBL8307119 | 0.81 | MAPT (0.59) | BACE1ALDH1A1RXFP1HTTLMNA | |
| SCHEMBL8305817 | 0.80 | ALDH1A1 (0.81) | BACE1ALDH1A1RXFP1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |