Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL8310130 | 0.98 | DGKA (0.57) | DGKAMAPTPAMLMNAALDH1A1 | |
| Chloroform SCHEMBL8309332 | 0.92 | TSHR (0.49) | DGKAMAPTPAMLMNAALDH1A1 | |
| SCHEMBL2145671 | 0.92 | DGKA (0.69) | DGKAMAPTPAMLMNAALDH1A1 | |
| SCHEMBL2181324 | 0.92 | DGKA (0.69) | DGKAMAPTPAMLMNAALDH1A1 | |
| SCHEMBL2182828 | 0.92 | DGKA (0.69) | DGKAMAPTPAMLMNAALDH1A1 | |
| SCHEMBL2183449 | 0.92 | DGKA (0.69) | DGKAMAPTPAMLMNAALDH1A1 | |
| SCHEMBL2217057 | 0.92 | DGKA (0.69) | DGKAMAPTPAMLMNAALDH1A1 | |
| SCHEMBL355564 | 0.92 | DGKA (0.69) | DGKAMAPTPAMLMNAALDH1A1 | |
| SCHEMBL6893576 | 0.90 | DGKA (0.65) | DGKAMAPTPAMLMNAALDH1A1 | |
| Chloroform SCHEMBL561913 | 0.85 | DGKA (0.64) | DGKAMAPTPAMLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914339-A | ANTI-DIABETIC AND/OR ANTIHYPERGLYCEMIA AND/OR ANTI-OBESITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0901484-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043273-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |