Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306762 | 0.86 | MEN1 (0.33) | MEN1KMT2AHTTL3MBTL1HCAR2 | |
| SCHEMBL8307263 | 0.81 | PTGS1 (0.39) | MEN1KMT2AHTTALDH1A1NPC1 | |
| SCHEMBL8308342 | 0.80 | ATM (0.33) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8303999 | 0.80 | MEN1 (0.34) | MEN1KMT2AHTTL3MBTL1HCAR2 | |
| SCHEMBL8881373 | 0.78 | KMT2A (0.35) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL9122354 | 0.76 | HCAR2 (0.33) | MEN1KMT2AHCAR2 | |
| Hydrochloric Acid SCHEMBL8303408 | 0.75 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL8306256 | 0.71 | MEN1 (0.33) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL9079804 | 0.70 | CYP1A2 (0.34) | L3MBTL1 | |
| SCHEMBL8309426 | 0.69 | CYP3A4 (0.42) | MEN1KMT2AHTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428053-A | Treats alzheimer's disease and other senile dementias | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | claimed |
| EP-0582182-B1 | 1-Aminoacetamidopyrroles and 1-amino-2-(substituted) pyrroles and their use for the treatment of neurodegenerative dysfunctions | HOECHST MARION ROUSSEL INC (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5605925-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-25 | — | — | US | disclosed |
| US-5576446-A | GLYCINE PARTIAL AGONIST AND ENHANCEMENT OF LEARNING AND MEMORY, TREATMENT OF ALZHEIMER'S | HOECHST MARION ROUSSEL, INC. (US) | 1996-11-19 | — | — | US | disclosed |
| US-5428053-A | Treats alzheimer's disease and other senile dementias | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0582182-A1 | 1-Aminoacetamidopyrroles and 1-amino-2-(substituted) pyrroles and their use for the treatment of neurodegenerative dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-02-09 | — | — | EP | disclosed |
| US-5274116-A | 1-aminoacetamidopyrroles and 1-aminoacetamido-2-(substituted)pyrroles and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-12-28 | — | — | US | disclosed |