Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309045 | 0.88 | TBXAS1 (0.60) | TBXAS1TSHR | |
| SCHEMBL9178744 | 0.87 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8310249 | 0.85 | TBXAS1 (0.62) | TBXAS1TSHR | |
| SCHEMBL8310093 | 0.84 | TBXAS1 (0.55) | TBXAS1TSHR | |
| SCHEMBL8309043 | 0.84 | TBXAS1 (0.77) | TBXAS1TSHR | |
| SCHEMBL8307370 | 0.83 | TBXAS1 (0.77) | TBXAS1TSHR | |
| SCHEMBL8305169 | 0.83 | TBXAS1 (0.53) | TBXAS1TSHR | |
| SCHEMBL8304634 | 0.83 | TBXAS1 (0.79) | TBXAS1TSHR | |
| SCHEMBL8304630 | 0.83 | TBXAS1 (0.60) | TBXAS1TSHR | |
| SCHEMBL8304728 | 0.83 | TBXAS1 (0.77) | TBXAS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579618-B1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1999-10-13 | — | — | EP | disclosed |
| US-5705523-A | THROMBOXANE A2 SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5457118-A | Pyridine derived agents for cardiovascular diseases | PFIZER INC. (US) | 1995-10-10 | — | — | US | disclosed |