Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.49 |
| ▸ | ZAP70 | P43403 | 6/20 | 0.48 |
| ▸ | PRKCA | P17252 | 2/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | PRKCB | P05771 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PRKCH | P24723 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300938 | 0.84 | ZAP70 (0.46) | ZAP70PRKCAPRKCDPRKD3EGFR | |
| SCHEMBL6947468 | 0.81 | CAMK2D (0.72) | CAMK2DZAP70PRKCAPRKCDPRKD3 | |
| SCHEMBL8306822 | 0.79 | ZAP70 (0.49) | ZAP70PRKCAPRKCDPRKD3EGFR | |
| 3-Chloroaniline SCHEMBL8308008 | 0.77 | CAMK2D (0.68) | CAMK2DZAP70PRKCAPRKCDPRKD3 | |
| SCHEMBL6957800 | 0.72 | ZAP70 (0.66) | CAMK2DZAP70PRKCAPRKCDPRKD3 | |
| SCHEMBL6957229 | 0.72 | ZAP70 (0.53) | ZAP70PRKCAPRKCDPRKD3EGFR | |
| SCHEMBL6955286 | 0.71 | ZAP70 (0.66) | CAMK2DZAP70PRKCAPRKCDPRKD3 | |
| SCHEMBL6952360 | 0.70 | ZAP70 (0.68) | CAMK2DZAP70PRKCAPRKCDPRKD3 | |
| SCHEMBL6952728 | 0.70 | ZAP70 (0.65) | CAMK2DZAP70PRKCAPRKCDPRKD3 | |
| SCHEMBL6955195 | 0.70 | ZAP70 (0.67) | CAMK2DZAP70PRKCAPRKCDPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934304-A1 | 2-PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998018782-A1 | 2-PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LIMITED (GB) | 1998-05-07 | — | — | WO | disclosed |