Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.61 |
| ▸ | PPARA | Q07869 | 14/20 | 0.61 |
| ▸ | PPARD | Q03181 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903189 | 0.85 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL7903503 | 0.84 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL8304446 | 0.84 | PPARG (0.66) | PPARGPPARAPPARD | |
| SCHEMBL7903445 | 0.82 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL8105089 | 0.82 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL7910024 | 0.79 | PPARG (0.66) | PPARGPPARAPPARD | |
| SCHEMBL5112238 | 0.79 | PPARG (0.76) | PPARGPPARAPPARD | |
| SCHEMBL8258850 | 0.79 | PPARG (0.78) | PPARGPPARAPPARD | |
| SCHEMBL7897441 | 0.78 | PPARG (0.81) | PPARGPPARAPPARD | |
| SCHEMBL4208383 | 0.78 | PPARG (0.61) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684242-B1 | ISOXAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | JAPAN TOBACCO INC (JP) | 1999-05-06 | — | — | EP | claimed |
| EP-0684242-B1 | ISOXAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | JAPAN TOBACCO INC (JP) | 1999-05-06 | — | — | EP | disclosed |