SCHEMBL8308399

SCHEMBL8308399

Fc1cccc(F)c1C1=NC(CCOc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)CO1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8892241 0.97 TAAR1 (0.46) TAAR1
SCHEMBL8892584 0.93 TAAR1 (0.43) TAAR1
SCHEMBL8892014 0.91 TAAR1 (0.40) TAAR1
SCHEMBL7803670 0.90 TAAR1 (0.37) TAAR1
SCHEMBL8309072 0.89 TAAR1 (0.43) TAAR1
SCHEMBL8892708 0.89 NOS1 (0.39) TAAR1
SCHEMBL8892742 0.89 TAAR1 (0.53) TAAR1
SCHEMBL8891995 0.87 TAAR1 (0.46) TAAR1
SCHEMBL8892138 0.86 TAAR1 (0.45) TAAR1
SCHEMBL8307005 0.85 TAAR1 (0.46) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639771-A PESTICIDES UBE INDUSTRIES, LTD. (JP) 1997-06-17 US claimed
EP-0912562-A1 HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1999-05-06 EP disclosed
EP-0655444-B1 Oxazoline derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same UBE INDUSTRIES (JP) 1999-01-27 EP disclosed
WO-1998003505-A2 HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-01-29 WO disclosed
US-5639771-A PESTICIDES UBE INDUSTRIES, LTD. (JP) 1997-06-17 US disclosed
EP-0655444-A1 Oxazoline derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same UBE INDUSTRIES, LTD. (JP) 1995-05-31 EP disclosed