Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18817861 | 0.90 | IDO1 (0.60) | IDO1FFAR1CTSVCTSLCTSS | |
| SCHEMBL29590253 | 0.87 | IDO1 (0.59) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL11142136 | 0.87 | IDO1 (0.59) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL8558598 | 0.85 | IDO1 (0.53) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL2175357 | 0.84 | IDO1 (0.61) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL30908530 | 0.84 | IDO1 (0.56) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL817976 | 0.84 | IDO1 (0.56) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL31072335 | 0.82 | IDO1 (0.50) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL27442086 | 0.81 | IDO1 (0.53) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL20102175 | 0.80 | IDO1 (0.51) | IDO1HTR2COPRM1DRD3AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105968289-B | Ultraviolet absorber-resistant polyurethane composition and coating material using the same | 东曹株式会社 | 2020-12-25 | — | — | CN | disclosed |
| EP-0904269-A1 | 3,4-DIARYL-2-HYDROXY-2,5-DIHYDROFURANS AS PRODRUGS TO COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1999-03-31 | — | — | EP | disclosed |
| WO-1997016435-A1 | 3,4-DIARYL-2-HYDROXY-2,5-DIHYDROFURANS AS PRODRUGS TO COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-05-09 | — | — | WO | disclosed |