Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308453 | 1.00 | PPARG (0.49) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8307062 | 0.91 | PPARG (0.55) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8305089 | 0.91 | PPARG (0.51) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8307060 | 0.91 | PPARG (0.55) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8305087 | 0.91 | PPARG (0.51) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8444587 | 0.89 | PPARG (0.51) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8309782 | 0.89 | PPARG (0.51) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8309781 | 0.89 | PPARG (0.51) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8309649 | 0.88 | PPARG (0.48) | PPARGFFAR1HTTMAPTS1PR1 | |
| SCHEMBL8309618 | 0.88 | PPARG (0.50) | PPARGFFAR1HTTMAPTS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |