Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.52 |
| ▸ | RXRG | P48443 | 15/20 | 0.51 |
| ▸ | RXRB | P28702 | 14/20 | 0.51 |
| ▸ | RARG | P13631 | 10/20 | 0.51 |
| ▸ | RARB | P10826 | 9/20 | 0.51 |
| ▸ | RARA | P10276 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308527 | 1.00 | RXRA (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8308540 | 1.00 | RXRA (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8310438 | 1.00 | RXRA (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8309071 | 0.88 | RXRA (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8309073 | 0.88 | RXRA (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8308333 | 0.88 | RXRA (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8308334 | 0.88 | RXRA (0.50) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8308682 | 0.86 | RXRA (0.53) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8307703 | 0.86 | RXRA (0.53) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8307705 | 0.86 | RXRA (0.53) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933351-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | claimed |
| EP-0800504-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | claimed |
| WO-1996020914-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-07-11 | — | — | WO | claimed |
| EP-0933350-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0933351-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0800504-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020914-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-07-11 | — | — | WO | disclosed |